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Prurigo simplex subacuta

Zuletzt geändert von Thomas Brinkmeier am 2025/04/25 21:40

Prurigo simplex subacuta

Engl: subacute prurigo

Vork: meist Frauen mittleren Alters

KL: - derbe, halbkugelige, Seropapeln, die stark jucken

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- Kratzen bis Blutaustritt (erst dann Erleichterung für den Pat.)

Lok: Prädilektionsstellen: Streckseiten der Extremitäten, Rücken, Glutealregion

Verl: schubweiser Verlauf über Monate oder Jahre

Prog: Abheilung mit atrophischen Narben und braunen Hyperpigmentierungen

Di: s. Pruritus

Hi: unspezifisch

Th: - Glukokortikoide

Appl: ggf. Folienokklusion

- lokale Antipruriginosa

- Zinkleimverbände

Ind: Köbnerisierung/Kratzaggravation

- Antihistaminika

- Cyclosporin A

Lit: J Dermatolog Treat 2003; 14: 48-50

- IFN-gamma

Lit: Acta Derm Venereol 1997; 77: 231-4

PT: CS

Dos: 1-8 Mio. U/Tag i.v. für 10-14 Tage

- Olanzapin

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Eig: Dopaminantagonist mit antihistaminergen und anticholinergen Eigenschaften

Pos: keine extrapyramidalen Nebenwirkungen, keine Kardiotoxizität

NW: Benommenheit, orthostatischer Kollaps, Mundtrockenheit, Cephalgien, Sehstörungen, Obstipation

Lit: Clin Exp Dermatol. 2006 May;31(3):464-5

PT: CS (4 Pat.)

Dos: 5 mg/Tag für 1 Woche, dann Dosiserhöhung auf 10 mg

- UV-Therapie

Bsp: Bade-PUVA

  
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